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Fuchs group

Principal investigator:
Im Neuenheimer Feld 280
69120 Heidelberg


General research interests and goals:

We use optogenetic tools to identify and characterize long-range GABAergic projections connecting functionally interacting brain regions. These brain regions are indispensable for the formation of episodic memories and spatial navigation (hippocampus, entorhinal cortex, medial septum) or motor coordination (motor cortex, striatum).

Current group members:

Associates: Dr. Roberta Pinna / Dr. Magdalene Schlesiger

Key publications:

Fuchs EC, Neitz A, Pinna R, Melzer S, Caputi A, Monyer H (2016) Local and distant input controlling excitation in layer II of the medial entorhinal cortex Neuron 89 (1):194-208 .
Melzer S, Michael M, Caputi A, Eliava M, Fuchs EC, Whittington MA, Monyer H (2012) Long-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex Science 335(6075):1506-10 .
Caputi A, Fuchs EC, Allen K, Le Magueresse C, Monyer H (2012) Selective reduction of AMPA currents onto hippocampal interneurons impairs network oscillatory activity PLoS One.7(6):e37318 .
Allen K, Fuchs EC, Jaschonek H, Bannerman DM, Monyer H (2011) Gap junctions between interneurons are required for normal spatial coding in the hippocampus and short-term spatial memory J Neurosci. 31(17):6542-52 .
Korotkova T, Fuchs EC, Ponomarenko A, von Engelhardt J, and Monyer H (2010) NMDA receptor ablation on parvalbumin-positive interneurons impairs hippocampal synchrony, spatial representations, and working memory. Neuron 68, 557-569 .